The Era of Personalized Cancer Therapeutics

  Isabel Levy & Seema Bachoo Glossary Adoptive T cell transfer, Allosteric site, Clonal expansion, CRISPR-Cas9, DNA, DNA sequencing, EGFR, ‘Gain-of-function’ mutation, Genome, Genomic Instability, GTPase, GDP, GTP, Kinase, ‘Loss-of-function’ mutation, MAPK signaling pathway, Mutation, Oncogene/Proto-oncogene,  Personalized Cancer Medicine, PI3K pathway, RAS, TP53 gene, Tumor suppressor gene   Background Cancer: a disease of the genome […]

The use of Stem Cells in Modern Medicine

Lovisa Lindquist   Abbreviations CNS, central nervous system; ESC, embryonic stem cell; FDA, Food & drug administration; HLA, human leukocyte antigen; HSC, hematopoietic stem cell; ICM, inner cell mass; iPSC, induced pluripotent stem cell; IVF, in vitro fertilization; MS, multiple sclerosis; MSC, mesenchymal stem cells; SC, stem cell Glossary Adipose tissue, Amniotic sac, Antigen, Autoimmune […]

What is CAR-T cell therapy?

Seema Bachoo   Immunotherapy is a type of cancer treatment that makes use of a patient’s own immune system to target and destroy cancer cells, with the aim of eliminating cancer from the body. There are several different types of immunotherapies. Cytokine-based immunotherapies harness the power of cytokines, which are soluble proteins that stimulate and […]

Pharmacogenomics: The future of medicine?

Celeste Cohen           Picture credit: National Human Genome Research Institute         Note: All terms shown in bold are defined in the glossary at the end of the article. Defining Pharmacogenomics From chemotherapy to HIV drugs, the past century has seen rapid advances in medical innovation, which have given rise to a wide range […]

In support of Breast Cancer Awareness month: Understanding the disease

Alessandro Troiani   “We all know our time is going to come eventually, but we rarely think about it, until we’re faced with the possibility of it.” This quote was taken from the testimonial of a patient who is referred to as PR in this article. PR was diagnosed with invasive breast cancer at the […]